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Get emergency help immediately if any of the following symptoms of overdose occur:

Agitation; confusion; convulsions (seizures); decreased reflexes; extreme drowsiness; high blood pressure; loss of memory; nausea; slurred speech; vomiting

Other side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. However, check with your doctor if any of the following side effects continue or are bothersome.

More common

Dryness of mouth; trembling or shaking of arms or legs

Less common or rare

Abdominal or stomach pain or discomfort; change in your sense of taste; constipation; diarrhea; dizziness; drowsiness; feeling of warmth of the face, neck, arms, and occasionally upper chest; heartburn or indigestion; increased or decreased appetite; increased sweating; joint or muscle pain; nightmares; trouble sleeping.

Other side effects not listed above may also occur in some patients. If you notice any other effects, check with your doctor.

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Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Stop taking this medicine and check with your doctor immediately if any combination of the following side effects occur:

Fast or racing heartbeat; pounding or irregular heartbeat; neck stiffness; severe throbbing headache which starts at the back of the head and radiates forward; slow heartbeat. Check with your doctor as soon as possible if any of the following side effects occur:

More common

Mild to moderate headache, or pressure in head

Less common

Anxiety; blurred vision or other changes in vision; dizziness, faintness, or lightheadedness, especially when getting up from a sitting or lying position; fast or racing heartbeat; high blood pressure; irritability; nervousness; pounding or irregular heartbeat; restlessness; unusual tiredness or weakness

Rare

Aggressive behavior; bleeding gums; burning, prickling, or tingling sensations; chest pain ; confusion; increased depression, or other mood and mental changes; difficulty in speaking; fast, slow, or irregular heart beat; feeling of something in the eye; general feeling of illness; headache (severe); increase in urination; increased sensitivity of eyes to light; irregular or prolonged menstrual periods; irritation or soreness of mouth; itching, redness, and swelling of eye; loss of balance control; loss of interest in self or surroundings; memory problems; pain or straining to pass urine or stool; painful urination; restlessness or desire to keep moving; ringing or noise in ears; seeing, hearing, or feeling something things that are not there; skin rash, hives, or itching; stomach pain or burning; slow heartbeat; troubled breathing; twisting movements of body; uncontrolled movements, especially of face, neck, and back

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When taken with certain drinks or other medicines, moclobemide and other monoamine oxidase inhibitors can cause very dangerous reactions such as sudden high blood pressure (also called hypertensive crisis). To avoid such reactions, obey the following rules of caution :

* Do not drink excessive amounts of alcohol.
* Do not take any other medicine unless approved or prescribed by your doctor. This especially includes nonprescription (over-the-counter [OTC]) medicine, such as that for colds (including nose drops or sprays), cough, hay fever, and appetite control; “keep awake” products; or products that make you sleepy.

Check with your doctor immediately if you experience any combination of the following symptoms: severe throbbing headache which starts at the back of the head and radiates forward, stiff neck, fast or racing heartbeat, pounding or irregular heartbeat, or slow heartbeat. These may be symptoms of a serious side effect that should have a doctor’s attention.

Do not stop taking this medicine without first checking with your doctor . Your doctor may want you to reduce gradually the amount you are using before stopping completely.

Dizziness, lightheadedness, or fainting may occur , especially when you get up from a lying or sitting position. Getting up slowly may help . When you get up from lying down, sit on the edge of the bed with your feet dangling for 1 or 2 minutes. Then stand up slowly. If the problem continues or gets worse, check with your doctor.

This medicine may cause blurred vision or make some people drowsy or less alert than they are normally. Make sure you know how you react to this medicine before you drive, use machines, or do anything else that could be dangerous if you are unable to see well or are not alert .

Before having any kind of surgery, dental treatment, or emergency treatment, tell the medical doctor or dentist in charge that you are using this medicine or have used it within the past 2 weeks . Taking moclobemide together with medicines that are used during surgery or dental or emergency treatments may increase the risk of serious side effects.

After you stop using this medicine, you must continue to exercise caution for at least 1 to 2 weeks concerning drink and other medicine, since these things may continue to react with moclobemide.

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Phenergan should not be given to a child younger than 2 years old. Phenergan can cause severe breathing problems or death in a child younger than 2. Carefully follow your doctor’s instructions when giving this medicine to a child of any age. Do not use Phenergan if you have asthma or other lung disease.

Before taking Phenergan, tell your doctor if you are allergic to any drugs, or if you have:

* epilepsy or another seizure disorder;
* sleep apnea (breathing stops during sleep);
* glaucoma;
* a stomach ulcer or digestive obstruction;
* bone marrow disorder;
* problems with urination;
* high blood pressure or heart disease; or
* liver disease.

If you have any of these conditions, you may need a dose adjustment or special tests to safely take promethazine.

FDA pregnancy category C. This medication may be harmful to an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant during treatment. It is not known whether Phenergan passes into breast milk or if it could harm an unborn baby. Do not use Phenergan without telling your doctor if you are breast-feeding a baby.

If you are over 60 years of age, you may be more sensitive to the side effects of Phenergan.

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