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Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

Call your doctor at once if you have any new or worsening symptoms such as: mood or behavior changes, anxiety, panic attacks, trouble sleeping, or if you feel impulsive, irritable, agitated, hostile, aggressive, restless, hyperactive (mentally or physically), more depressed, or have thoughts about suicide or hurting yourself.

Call your doctor at once if you have any of these serious side effects:

* fast, pounding, or uneven heart rate;
* confusion, hallucinations, or seizure (convulsions);
* easy bruising or bleeding, unusual weakness;
* feeling light-headed, fainting;
* restless muscle movements in your eyes, tongue, jaw, or neck;
* tremors or uncontrollable shaking;
* urinating less than usual or not at all; or
* extreme thirst with headache, nausea, vomiting, and weakness.

Less serious side effects may include:

* nausea, vomiting, constipation, loss of appetite;
* dry mouth;
* weight changes;
* weakness, lack of coordination;
* numbness or tingly feeling;
* feeling dizzy, drowsy, or tired;
* sleep problems (insomnia), nightmares;
* blurred vision, headache, ringing in your ears;
* increased sweating;
* breast swelling (in men or women); or
* decreased sex drive, impotence, or difficulty having an orgasm.

This is not a complete list of side effects and others may occur. Tell your doctor about any unusual or bothersome side effect.

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Do not use this medication if you are allergic to Sinequan, or if you have glaucoma or problems with urination. Do not use Sinequan if you have used an MAO inhibitor such as isocarboxazid (Marplan), phenelzine (Nardil), rasagiline (Azilect), selegiline (Eldepryl, Emsam), or tranylcypromine (Parnate) within the past 14 days. Serious, life-threatening side effects can occur if you take Sinequan before the MAO inhibitor has cleared from your body.

Before taking Sinequan, tell your doctor if you are allergic to any drugs, or if you have:

* bipolar disorder (manic-depression); or
* diabetes (Sinequan may raise or lower blood sugar).

If you have any of these conditions, you may need a dose adjustment or special tests to safely take this medication.

You may have thoughts about suicide while taking an antidepressant, especially if you are younger than 24 years old. Tell your doctor if you have worsening depression or suicidal thoughts during the first several weeks of treatment, or whenever your dose is changed.

Your family or other caregivers should also be alert to changes in your mood or symptoms. Your doctor will need to check you at regular visits for at least the first 12 weeks of treatment.

This medication may be harmful to an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant during treatment. It is not known whether Sinequan passes into breast milk or if it could harm a nursing baby. Do not use this medication without telling your doctor if you are breast-feeding a baby. Do not give Sinequan to anyone younger than 18 years old without the advice of a doctor.

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Do not use this medication if you are allergic to Sinequan, or if you have glaucoma or problems with urination. Do not use Sinequan if you have used an MAO inhibitor such as isocarboxazid (Marplan), phenelzine (Nardil), rasagiline (Azilect), selegiline (Eldepryl, Emsam), or tranylcypromine (Parnate) within the past 14 days. Serious, life-threatening side effects can occur if you take Sinequan before the MAO inhibitor has cleared from your body.

You may have thoughts about suicide when you first start taking an antidepressant, especially if you are younger than 24 years old. Your doctor will need to check you at regular visits for at least the first 12 weeks of treatment.

Call your doctor at once if you have any new or worsening symptoms such as: mood or behavior changes, anxiety, panic attacks, trouble sleeping, or if you feel impulsive, irritable, agitated, hostile, aggressive, restless, hyperactive (mentally or physically), more depressed, or have thoughts about suicide or hurting yourself.

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Get emergency medical help if you have any of these signs of an allergic reaction: skin rash or hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

Call your doctor at once if you have any new or worsening symptoms such as: mood or behavior changes, anxiety, panic attacks, trouble sleeping, or if you feel impulsive, irritable, agitated, hostile, aggressive, restless, hyperactive (mentally or physically), more depressed, or have thoughts about suicide or hurting yourself.

Call your doctor at once if you have any of these serious side effects:

* fever, chills, body aches, flu symptoms;
* white patches or sores inside your mouth or on your lips; or
* feeling like you might pass out.

Less serious side effects include:

* drowsiness, dizziness, weakness;
* nausea, stomach pain;
* constipation;
* increased appetite, weight gain;
* dry mouth; or
* thirst.

This is not a complete list of side effects and others may occur. Tell your doctor about any unusual or bothersome side effect.

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Get emergency medical help if you have any of these signs of an allergic reaction: skin rash or hives; difficulty breathing; swelling of your face, lips, tongue, or throat. Contact your doctor promptly if you have any of the following side effects, especially if they are new symptoms or if they get worse: mood changes, anxiety, panic attacks, trouble sleeping, irritability, agitation, aggressiveness, severe restlessness, mania (mental and/or physical hyperactivity), thoughts of suicide or hurting yourself.

Call your doctor at once if you have any of these serious side effects:

* seizure (convulsions);
* tremors, shivering, muscle stiffness or twitching;
* problems with balance or coordination;
* agitation, confusion, sweating, fast heartbeat; or
* easy bruising or bleeding (such as a nosebleed).

Less serious side effects may include:

* feeling nervous, restless, or unable to sit still;
* drowsiness, dizziness, weakness;
* sleep problems (insomnia);
* nausea, constipation, loss of appetite;
*  weight changes;
* decreased sex drive, impotence, or difficulty having an orgasm; or
* dry mouth, yawning, or ringing in your ears.

This is not a complete list of side effects and others may occur. Tell your doctor about any unusual or bothersome side effect.

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Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

Call your doctor at once if you have any new or worsening symptoms such as: mood or behavior changes, anxiety, panic attacks, trouble sleeping, or if you feel impulsive, irritable, agitated, hostile, aggressive, restless, hyperactive (mentally or physically), more depressed, or have thoughts about suicide or hurting yourself.

Call your doctor at once if you have any of these serious side effects:

* fast, pounding, or uneven heart rate;
* chest pain or heavy feeling, pain spreading to the arm or shoulder, nausea, sweating, general ill feeling;
* sudden numbness or weakness, especially on one side of the body;
* sudden headache, confusion, problems with vision, speech, or balance;
* confusion, hallucinations, or seizure (convulsions);
* easy bruising or bleeding, unusual weakness;
* restless muscle movements in your eyes, tongue, jaw, or neck;
* tremors;
* extreme thirst with headache, nausea, vomiting, and weakness;
* feeling light-headed or fainting; or
* urinating less than usual or not at all.

Less serious side effects may include:

* nausea, vomiting, stomach pain, loss of appetite;
* constipation or diarrhea;
*  weight changes;
* dry mouth, unpleasant taste;
* weakness, lack of coordination;
* numbness or tingly feeling;
* blurred vision, headache, ringing in your ears;
* mild skin rash;
* breast swelling (in men or women); or
* increased sweating.

This is not a complete list of side effects and others may occur. Tell your doctor about any unusual or bothersome side effect.

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Do not use this medication if you are allergic to Pamelor, or if you have recently had a heart attack. Do not use Pamelor if you have used an MAO inhibitor such as isocarboxazid (Marplan), phenelzine (Nardil), rasagiline (Azilect), selegiline (Eldepryl, Emsam), or tranylcypromine (Parnate) within the past 14 days. Serious, life-threatening side effects can occur if you take Pamelor before the MAO inhibitor has cleared from your body.

Before taking Pamelor, tell your doctor if you are allergic to any drugs, or if you have:

* heart disease;
* a history of heart attack, stroke, or seizures;
* bipolar disorder (manic-depression);
* schizophrenia or other mental illness;
* diabetes (Pamelor may raise or lower blood sugar);
* overactive thyroid;
* glaucoma; or
* problems with urination.

If you have any of these conditions, you may need a dose adjustment or special tests to safely take Pamelor.

You may have thoughts about suicide when you first start taking an antidepressant, especially if you are younger than 24 years old. Tell your doctor if you have worsening symptoms of depression or suicidal thoughts during the first several weeks of treatment, or whenever your dose is changed.

Your family or other caregivers should also be alert to changes in your mood or symptoms. Your doctor will need to check you at regular visits for at least the first 12 weeks of treatment.

This medication may be harmful to an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant during treatment. It is not known whether Pamelor passes into breast milk or if it could harm a nursing baby. Do not use this medication without telling your doctor if you are breast-feeding a baby.

Older adults may be more likely to have side effects from this medication. Do not give this medication to anyone under 18 years old without the advice of a doctor.

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In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For moclobemide, the following should be considered:

* Allergies—Tell your doctor if you have ever had any unusual or allergic reaction to moclobemide or monoamine oxidase inhibitors. Also tell your doctor and pharmacist if you are allergic to any other substances, such as foods, preservatives, or dyes.

* Pregnancy—Studies of moclobemide use in pregnant women have not been done. In some animal studies, weight gain was decreased in pregnant females or their offspring after high doses of moclobemide. Before taking this medicine, make sure your doctor knows if you are pregnant or if you may become pregnant.

* Breast-feeding—Small quantities of moclobemide pass into the breast milk. Moclobemide is not recommended during breast-feeding, because it may cause unwanted effects in nursing babies.

* Children—Studies on moclobemide have been done only in adult patients, and there is no specific information comparing use of moclobemide in children with use in other age groups.

* Older adults—Older adults are especially sensitive to the effects of moclobemide. This may increase the chance of side effects during treatment. Dizziness or lightheadedness may be especially likely to occur in elderly patients, who are usually more sensitive than younger adults to these effects.

* Other medicines—Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. When you are taking moclobemide, it is especially important that your doctor and pharmacist know if you are taking any of the following:

* Amphetamines or
* Appetite suppressants (diet pills) or
* Dextromethorphan or
* Medicine for asthma or other breathing problems
* Medicines for colds, sinus problems, or hay fever or other allergies (including nose drops or sprays) or
* Meperidine (e.g., Demerol) or
* Selective serotonin reuptake inhibitor antidepressants (fluvoxamine [e.g., Luvox], fluoxetine [e.g., Prozac], paroxetine [e.g., Paxil], sertraline [e.g., Zoloft]) or
* Tricyclic antidepressants (amitriptyline [e.g., Elavil], amoxapine [e.g., Asendin], clomipramine [e.g., Anafranil], desipramine [e.g., Norpramin], doxepin [e.g., Sinequan], imipramine [e.g., Tofranil], nortriptyline [e.g., Aventyl], protriptyline [e.g., Vivactil], trimipramine [e.g., Surmontil]—Using these medicines together may increase the chance of serious side effects
* Cimetidine (e.g., Tagamet)—May increase the effect of moclobemide; moclobemide doses may need to be lowered by approximately 50% in patients using cimetidine
* Monoamine oxidase (MAO) inhibitor activity (isocarboxazid [e.g., Marplan], phenelzine [e.g., Nardil], procarbazine [e.g., Matulane], selegiline [e.g., Eldepryl], tranylcypromine [e.g., Parnate])—Taking moclobemide while you are taking or within 2 weeks of taking monoamine oxidase (MAO) inhibitors may cause very serious side effects, such as sudden high body temperature, extremely high blood pressure, and severe convulsions; at least 14 days should be allowed between stopping treatment with one medicine and starting treatment with the other

* Other medical problems—The presence of other medical problems may affect the use of moclobemide. Make sure you tell your doctor if you have any other medical problems, especially:

* Hypertension—Moclobemide may make the problem worse
* Liver disease—Effects of moclobemide may be increased because of slower removal of the medicine from the body; your doctor may need to change your dose.

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Get emergency medical help if you have any of these signs of an allergic reaction: skin rash or hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

Call your doctor at once if you have any new or worsening symptoms such as: mood or behavior changes, anxiety, panic attacks, trouble sleeping, or if you feel impulsive, irritable, agitated, hostile, aggressive, restless, hyperactive (mentally or physically), depressed, or have thoughts about suicide or hurting yourself.

Call your doctor at once if you have a serious side effect such as:

* seizure (convulsions);
* unusual thoughts or behavior;
* anxiety, restlessness, memory problems, trouble concentrating, hallucinations, feeling like you might pass out;
* high fever, chills or goose bumps, loss of coordination, overactive reflexes, stiff muscles; or
* confusion, sweating, fast or uneven heartbeats, and rapid breathing.

Less serious side effects may include:

* loss of appetite, weight loss;
* dry mouth, mild nausea or upset stomach, diarrhea, constipation;
* sleep problems (insomnia);
* dizziness, drowsiness;
* decreased sex drive, impotence, trouble having an orgasm; or
* unusual dreams.

This is not a complete list of side effects and others may occur. Tell your doctor about any unusual or bothersome side effect.

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Do not take this medication if you are allergic to Luvox, or if you are also taking alosetron (Lotronex), tizanidine (Zanaflex), thioridazine (Mellaril), pimozide (Orap), or an MAO inhibitor such as isocarboxazid (Marplan), tranylcypromine (Parnate), phenelzine (Nardil), rasagiline (Azilect), or selegiline (Eldepryl, Emsam). Some of these medications can cause serious or life-threatening drug interactions when taken within 14 days before or after taking Luvox.

You may have thoughts about suicide when you first start taking an this medication, especially if you are younger than 24 years old. Your doctor will need to check you at regular visits for at least the first 12 weeks of treatment.

Call your doctor at once if you have any new or worsening symptoms such as: mood or behavior changes, anxiety, panic attacks, trouble sleeping, or if you feel impulsive, irritable, agitated, hostile, aggressive, restless, hyperactive (mentally or physically), depressed, or have thoughts about suicide or hurting yourself. There are many other medicines that can cause serious medical problems if you take them together with Luvox. Tell your doctor about all the prescription and over-the-counter medications you use. This includes vitamins, minerals, herbal products, and drugs prescribed by other doctors. Do not start using a new medication without telling your doctor. Keep a list with you of all the medicines you use and show this list to any doctor or other healthcare provider who treats you.

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